Klinefelter Syndromes
《英文msh詞典》Klinefelter Syndromes
[入口詞] Klinefelter Syndromes
[主題詞] Klinefelter Syndrome
[英文釋義] A SEX CHROMOSOME DISORDER characterized by small testes,underdevelopment of secondary sexual characteristics,infertility (INFERTILITY,MALE),hyalinization and fibrosis of the seminiferous tubules,and elevated levels of gonadotropin. Patients tend to have long legs and a slim,tall stature. GYNECOMASTIA is present in many of the patients. The classic form has the karyotype 47,XXY. Several variants include those with the karyotpes 48,XXYY; 48,XXXY; 49,XXXXY,and several mosaic patterns ( 46,XY/47,XXY; 47,XXY/48,XXXY,etc.).